Designing and Engineering of Artificial Microbial Consortia (AMC) for Bioprocess: Application Appro (2024-02-15)

About Workshop:
The workshop on Designing and Engineering of Artificial Microbial Consortia (AMC) for Bioprocess: Application Approaches aims to provide a comprehensive understanding of the principles and techniques involved in constructing and optimizing artificial microbial consortia for bioprocessing applications. Participants will delve into the intricate world of microbial interactions, exploring design strategies, and engineering approaches to tailor microbial communities for specific biotechnological tasks. The workshop will cover diverse applications, ranging from environmental remediation to biofuel production.Through a combination of lectures, case studies for sustainable bioproduction.

Aim: The aim of the workshop on Designing and Engineering of Artificial Microbial Consortia (AMC) for Bioprocess: Application Approaches is to equip participants with a comprehensive understanding of the principles and methodologies involved in the design and optimization of artificial microbial consortia for diverse bioprocessing applications. The workshop seeks to foster expertise in the manipulation of microbial communities through engineering strategies, enabling participants to apply this knowledge to address real-world challenges in fields such as environmental remediation, biofuel production, and other biotechnological processes. Through a combination of theoretical knowledge, the workshop aims to empower participants to contribute to the advancement of sustainable bioproduction by effectively designing and engineering artificial microbial consortia tailored to specific application needs.

Workshop Objectives:

• Enhance Environmental Remediation Skills: Equip participants with the knowledge and skills to design microbial consortia for environmental remediation purposes, addressing challenges such as pollutant degradation and soil or water restoration.
• Optimize Biofuel Production: Provide insights into engineering microbial consortia for improved biofuel production, focusing on metabolic engineering strategies and the optimization of pathways involved in bioenergy synthesis.
• Facilitate Waste Conversion: Explore applications of artificial microbial consortia in waste conversion processes, guiding participants in designing consortia capable of efficient organic waste degradation and conversion into valuable products.
• Improve Agricultural Bioprocessing: Demonstrate the application of microbial consortia in agricultural bioprocessing, such as biofertilizer production or plant growth promotion, by optimizing nutrient cycling and enhancing soil microbial communities.
• Address Industrial Biomanufacturing Challenges: Provide solutions to challenges in industrial biomanufacturing by teaching participants how to engineer microbial consortia for the production of chemicals, enzymes, and other bio-based products.
• Develop Sustainable Bioprocesses: Encourage participants to focus on the sustainability aspects of bioprocessing by designing microbial consortia that reduce resource inputs, minimize waste generation, and enhance overall process efficiency.
• Explore Medical and Healthcare Applications: Introduce the potential of microbial consortia in medical and healthcare applications, including the development of probiotics and engineered microbial communities for therapeutic purposes.

What you will learn?

Day 1: Concept, designing and engineering of AMC for industrial bioprocesses

• Potential of AMC for the improvement of established microbial consortium
• AMC based novel processes for bioproduction of platform chemicals, biofuels, or
  pharmaceutical compounds.
• AMC platform for co-cultures, exploration of the interaction mechanisms for the
  optimization of product enhancement factors
• AMC based solution to bioprocesses that fundamentally face metabolic restrictions or
  kinetic limitations

Day 2: Parameter optimization, volumetric expansion and product yields for AMC based bioproduction of high value platform chemicals from wastes

• Design and engineering of AMC as per the substrate profile without compromising the
  product yields
• Volumetric expansion of fermentation, AMC and optimization of eco-biotechnological
  parameters
• Identification of bioprocess space (ecological niche) & analysis of meta-data of
  microbial physiologies for the selection of microorganisms

Day 3: Challenges with designing of individual pure cultures, mutual medium and scale up processes

• Design of eco-biotechnological conditions (bioprocess parameters) for cultivating the
  individual pure cultures
• Designing of mutual medium and optimization in the eco-physiological section
• Scale up Industrial challenges