Protein Structure Prediction and Validation in Structural Biology
Unlocking the Secrets of Proteins: Predict and Validate with Precision
Online/ e-LMS
Self Paced
Moderate
1 Month
About
The “Protein Structure Prediction and Validation in Structural Biology” program offers an in-depth exploration into the methodologies and technologies used to determine the three-dimensional structures of proteins. This program delves into various computational approaches such as homology modeling, threading, and ab initio modeling, emphasizing the importance of structural accuracy and validation techniques. Participants will learn about the significance of protein structures in understanding biological functions and developing therapeutic interventions.
Throughout this one-month program, participants will engage in hands-on sessions, utilizing advanced software and databases to predict protein structures and validate their accuracy through techniques such as X-ray crystallography and NMR spectroscopy. The curriculum is designed to provide a comprehensive understanding of the structural biology field, fostering the skills required for both academic research and industrial applications. By the end of the program, participants will be proficient in using bioinformatics tools and understanding the practical applications of protein structure prediction in drug discovery and biotechnology.
Aim
To equip participants with the knowledge and skills necessary to predict and validate protein structures, leveraging cutting-edge computational tools and techniques in structural biology.
Program Objectives
- Understand the fundamental concepts of protein structure prediction.
- Gain proficiency in using computational tools for protein modeling.
- Learn techniques for validating protein structures.
- Explore the applications of protein structure prediction in drug discovery.
- Develop practical skills through hands-on experience with relevant software and databases.
Program Structure
Module 1
- Protein and their interaction with ligand
- Overview of protein 3D structure file format
- Overview of small molecule databases
Tools:
- PubChem/Drug Bank/Zinc Database
- Protein Data Bank (PDB)/PDBSum
Module 2
- Comparative modeling/homology modeling
- Protein 3D structure Prediction based on homology
- Ab initio structure prediction
Tools: Modeller & Online tools
Module 3
- Structure validation
- Protein Structure validation
- Ramachandran plot
Tools: SAVES server
Participant’s Eligibility
- Undergraduate degree in Biochemistry, Molecular Biology, Bioinformatics, or related fields.
- Professionals in biotechnology, pharmaceutical, or research industries.
- Individuals with a keen interest in structural biology and computational biology.
Program Outcomes
- Proficiency in predicting protein structures using various computational methods.
- Ability to validate protein structures through experimental techniques.
- Understanding the role of protein structures in biological processes and drug design.
- Hands-on experience with bioinformatics tools and databases.
- Enhanced skills for careers in structural biology and related fields.
Fee Structure
Standard Fee: INR 4,998 USD 110
Discounted Fee: INR 2499 USD 55
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List of CurrenciesBatches
Certificate
Program Assessment
Certification to this program will be based on the evaluation of following assignment (s)/ examinations:
Exam | Weightage |
---|---|
Mid Term Assignments | 50 % |
Project Report Submission (Includes Mandatory Paper Publication) | 50 % |
To study the printed/online course material, submit and clear, the mid term assignments, project work/research study (in completion of project work/research study, a final report must be submitted) and the online examination, you are allotted a 1-month period. You will be awarded a certificate, only after successful completion/ and clearance of all the aforesaid assignment(s) and examinations.
Program Deliverables
- Access to e-LMS
- Real Time Project for Dissertation
- Project Guidance
- Paper Publication Opportunity
- Self Assessment
- Final Examination
- e-Certification
- e-Marksheet
Future Career Prospects
- Structural Biologist
- Bioinformatics Specialist
- Drug Discovery Scientist
- Computational Biologist
- Protein Chemist
- Research Scientist in academia or industry
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