Self Paced

Protein Structure Prediction and Validation in Structural Biology

Unlocking the Secrets of Proteins: Predict and Validate with Precision

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MODE
Online/ e-LMS
TYPE
Self Paced
LEVEL
Moderate
DURATION
1 Month

About

The “Protein Structure Prediction and Validation in Structural Biology” program offers an in-depth exploration into the methodologies and technologies used to determine the three-dimensional structures of proteins. This program delves into various computational approaches such as homology modeling, threading, and ab initio modeling, emphasizing the importance of structural accuracy and validation techniques. Participants will learn about the significance of protein structures in understanding biological functions and developing therapeutic interventions.

Throughout this one-month program, participants will engage in hands-on sessions, utilizing advanced software and databases to predict protein structures and validate their accuracy through techniques such as X-ray crystallography and NMR spectroscopy. The curriculum is designed to provide a comprehensive understanding of the structural biology field, fostering the skills required for both academic research and industrial applications. By the end of the program, participants will be proficient in using bioinformatics tools and understanding the practical applications of protein structure prediction in drug discovery and biotechnology.

Aim

To equip participants with the knowledge and skills necessary to predict and validate protein structures, leveraging cutting-edge computational tools and techniques in structural biology.

Program Objectives

  • Understand the fundamental concepts of protein structure prediction.
  • Gain proficiency in using computational tools for protein modeling.
  • Learn techniques for validating protein structures.
  • Explore the applications of protein structure prediction in drug discovery.
  • Develop practical skills through hands-on experience with relevant software and databases.

Program Structure

Module 1

  • Protein and their interaction with ligand
  • Overview of protein 3D structure file format
  • Overview of small molecule databases

Tools:

  • PubChem/Drug Bank/Zinc Database
  • Protein Data Bank (PDB)/PDBSum

Module 2

  • Comparative modeling/homology modeling
  • Protein 3D structure Prediction based on homology
  • Ab initio structure prediction

Tools: Modeller & Online tools

Module 3

  • Structure validation
  • Protein Structure validation
  • Ramachandran plot

Tools: SAVES server

Participant’s Eligibility

  • Undergraduate degree in Biochemistry, Molecular Biology, Bioinformatics, or related fields.
  • Professionals in biotechnology, pharmaceutical, or research industries.
  • Individuals with a keen interest in structural biology and computational biology.

Program Outcomes

  • Proficiency in predicting protein structures using various computational methods.
  • Ability to validate protein structures through experimental techniques.
  • Understanding the role of protein structures in biological processes and drug design.
  • Hands-on experience with bioinformatics tools and databases.
  • Enhanced skills for careers in structural biology and related fields.


Fee Structure

Standard Fee:           INR 4,998           USD 110

Discounted Fee:       INR 2499             USD 55

Batches

Spring
Summer

Autumn
Winter

Certificate

Program Assessment

Certification to this program will be based on the evaluation of following assignment (s)/ examinations:

Exam Weightage
Mid Term Assignments 20 %
Final Online Exam 30 %
Project Report Submission (Includes Mandatory Paper Publication) 50 %

To study the printed/online course material, submit and clear, the mid term assignments, project work/research study (in completion of project work/research study, a final report must be submitted) and the online examination, you are allotted a 1-month period. You will be awarded a certificate, only after successful completion/ and clearance of all the aforesaid assignment(s) and examinations.

Program Deliverables

  • Access to e-LMS
  • Real Time Project for Dissertation
  • Project Guidance
  • Paper Publication Opportunity
  • Self Assessment
  • Final Examination
  • e-Certification
  • e-Marksheet

Future Career Prospects

  • Structural Biologist
  • Bioinformatics Specialist
  • Drug Discovery Scientist
  • Computational Biologist
  • Protein Chemist
  • Research Scientist in academia or industry

Enter the Hall of Fame!

Take your research to the next level!

Publication Opportunity
Potentially earn a place in our coveted Hall of Fame.

Centre of Excellence
Join the esteemed Centre of Excellence.

Networking and Learning
Network with industry leaders, access ongoing learning opportunities.

Hall of Fame
Get your groundbreaking work considered for publication in a prestigious Open Access Journal (worth ₹20,000/USD 1,000).

Achieve excellence and solidify your reputation among the elite!


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