CRISPR-Cas Genome Editing: Mechanisms and Applications
Mastering Gene Editing: Unlock the Potential of CRISPR
Early access to e-LMS included
About This Course
The CRISPR-Cas Defense Mechanism program delves into the revolutionary gene-editing technology that has transformed scientific research and biotechnology. Over the course of one month, students will learn about different CRISPR-Cas systems, their discovery, and how they can be harnessed for genome editing across various organisms. The curriculum is designed to cover both theoretical concepts and practical applications, including lab simulations and case studies of CRISPR in therapeutic settings and agriculture.
Aim
This program aims to provide an in-depth understanding of the CRISPR-Cas systems, highlighting their roles in microbial immunity and biotechnological applications. Participants will explore the molecular mechanisms, ethical implications, and the latest advancements in CRISPR technology to prepare for careers in genetic engineering and biomedicine.
Program Objectives
- Understand the fundamentals of CRISPR-Cas systems and their biological functions.
- Gain hands-on experience with CRISPR design and applications in lab simulations.
- Explore the ethical and regulatory frameworks governing gene editing.
- Analyze case studies on the impact of CRISPR technologies in medicine and agriculture.
- Prepare for advanced studies or careers in genetic editing technologies.
Program Structure
Week 1: CRISPR-Cas Systems – Origins and Molecular Biology
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Discovery of CRISPR in microbial adaptive immunity
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Mechanisms of Cas9, Cas12, and Cas13 nucleases
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Guide RNA design and PAM site recognition
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DNA repair pathways: HDR vs. NHEJ
Week 2: Genome Editing Platforms and Delivery Technologies
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Plasmid, RNP, and viral vector delivery methods
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Off-target effects and specificity optimization
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Deep tech delivery tools: lipid nanoparticles, electroporation
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Multiplex genome editing and gene knock-in strategies
Week 3: CRISPR in Research, Medicine, and Agriculture
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Functional genomics and model organism editing
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Therapeutic applications: cancer, blood disorders, viral diseases
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Crop improvement and gene drive in agriculture
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Real-world case studies and translational breakthroughs
Week 4: Future of CRISPR, Ethics, and Regulation
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Prime editing, base editing, and epigenome modulation
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CRISPR diagnostics (e.g., SHERLOCK, DETECTR platforms)
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Bioethical considerations and global regulatory landscape
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Commercial trends, patent battles, and innovation pipelines
Who Should Enrol?
- Undergraduate degree in Molecular Biology, Biotechnology, Genetics, or related fields.
- Professionals in biomedical research, pharmaceuticals, or agricultural biotechnology.
- Individuals with a keen interest in genetic engineering and genome editing technologies.
Program Outcomes
- Proficiency in CRISPR-Cas technology applications
- Understanding of molecular techniques in genetic engineering
- Ability to address ethical considerations in biotech
- Readiness for advanced research or professional roles
- Skills in interdisciplinary collaboration and innovation
Fee Structure
Standard: ₹8,998 | $198
Discounted: ₹4499 | $99
We accept 20+ global currencies. View list →
What You’ll Gain
- Full access to e-LMS
- Real-world dry lab projects
- 1:1 project guidance
- Publication opportunity
- Self-assessment & final exam
- e-Certificate & e-Marksheet
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