Short Courses

Computer Aided Drug Design in Taste Masking (CADD)

Computer-Aided Drug Design, Taste Masking, Pharmaceutical Development, Patient Compliance, Formulation Approaches, Bitter Taste Modulation, Taste Receptor Interactions, In Silico Models

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MODE
Virtual (Google Meet)
TYPE
Self Paced
LEVEL
Moderate
DURATION
1.5 Hours/ Day
VIDEO LENGTH
1

About

The Computer-Aided Drug Design in Taste Masking (CADD) program integrates computational methods with pharmaceutical science to tackle the challenge of improving the taste of medications. Leveraging advanced modeling techniques, participants delve into the intricate molecular structures of drugs, aiming to design formulations that effectively mask their bitter taste. Through virtual screening and structure-activity relationship analysis, the program seeks to identify novel compounds or optimize existing ones, ensuring they not only retain their therapeutic efficacy but also become more palatable for patients, especially for those with sensitive taste buds such as children and the elderly. By combining the power of computational approaches with pharmaceutical innovation, this program contributes to enhancing patient satisfaction and medication adherence, ultimately improving healthcare outcomes.

Aim

The aim of the “Computer Aided Drug Design in Taste Masking (CADD)” program is to utilize computational methods and modeling techniques to design pharmaceutical compounds with improved taste masking properties. By leveraging computer-aided drug design (CADD) approaches, the program seeks to identify and optimize candidate molecules that effectively mask the bitter taste of pharmaceutical drugs, making them more palatable and acceptable for patients, particularly in pediatric or geriatric populations. Through a combination of molecular modeling, virtual screening, and structure-activity relationship (SAR) analysis, the program aims to expedite the discovery and development of taste-masked formulations, ultimately enhancing patient compliance, adherence to medication regimens, and therapeutic outcomes.

Courses Objectives

  • Provide an overview of taste masking challenges in drug development and the importance of patient-centric formulation approaches.
  • Introduce participants to the principles and techniques of computer-aided drug design and its application in taste masking.
  • Share insights into the latest computational tools, methodologies, and software platforms used in taste masking studies.
  • Highlight successful case studies and real-world examples where CADD has facilitated the development of palatable medications.
  • Foster collaboration and knowledge exchange among participants from academia, industry, and regulatory bodies.
  • Identify future research directions and opportunities in the field of taste masking through CADD.

Courses Structure

Day 1: Introduction to Computer-Aided Drug Design and Taste Masking
 Basics of Drug Design and Taste Masking

  • Introduction to computer-aided drug design (CADD) and its applications in pharmaceutical research 
  • Overview of taste masking techniques and their importance in enhancing patient acceptability 
  • Challenges and considerations in taste masking of pharmaceutical compounds

Principles of Taste Perception and Evaluation

  • Understanding the physiology of taste perception 
  • Techniques for evaluating taste perception and masking efficacy
  • Case studies highlighting successful taste masking strategies 

Computational Techniques in Drug Design 

  • Introduction to molecular modeling and simulation methods 
  • Structure-based drug design approaches for taste masking
  • Virtual screening and ligand-based drug design techniques

Day 2: Computational Tools and Techniques for Taste Masking

Molecular Docking and Binding Analysis 

  • Principles of molecular docking and its role in predicting drug-target interactions
  • Hands-on session using molecular docking software to identify potential taste masking agents 

In Silico Formulation Design and Optimization 

  • Overview of in silico formulation design techniques 
  • Predictive modeling for optimizing drug release and taste masking in different dosage forms
  • Case studies illustrating successful in silico formulation design approaches

Day 3: Case Studies 

Case Studies on Taste Masking in Various Drug Delivery Systems

  • Application of computer-aided drug design in taste masking for oral solid dosage forms, liquids
  • Evaluation of taste masking efficacy using computational methods

Interactive Discussion and Future Trends

  • Open forum for participants to share their experiences and challenges in taste masking research
  • Discussion on emerging trends and future directions in computer-aided taste masking

Participant’s Eligibility

  1. Educational Background: Participants may be required to have a background in pharmaceutical sciences, medicinal chemistry, pharmacology, computational chemistry, or a related field at the undergraduate or graduate level.
  2. Research Experience: Some programs may prefer participants with prior research experience in drug design, computational chemistry, pharmaceutical formulation, or taste masking techniques.
  3. Computer Skills: Proficiency in computer programming languages (e.g., Python, R), molecular modeling software (e.g., Schrödinger, MOE, AutoDock), and statistical analysis tools may be beneficial for effective participation in the program.
  4. Interest and Motivation: Individuals with a strong interest in drug discovery, pharmaceutical formulation, and computational methods, as well as a commitment to advancing their skills and knowledge in these areas, are typically encouraged to apply.
  5. Language Proficiency: Depending on the language of instruction and communication, participants may be required to demonstrate proficiency in the relevant language(s), typically English.

Important Dates

Registration Ends

2023-06-24
Indian Standard Timing 02:00 PM

Courses Dates

2023-06-24 to 2023-06-26
Indian Standard Timing 03:00 PM

Courses Outcomes

  • In-depth Understanding of Taste Masking Principles
  • Knowledge of Computer-Aided Drug Design (CADD) Techniques
  • Familiarity with Innovative Taste Masking Strategies
  • Insight into Current Research and Advancements
  • Improved Drug Formulation and Patient Adherence


Fee Structure

Student

INR. 1199
USD. 40

Ph.D. Scholar / Researcher

INR. 1499
USD. 45

Academician / Faculty

INR. 1999
USD. 55

Industry Professional

INR. 2499
USD. 80

Standard Fee:           INR 11,998           USD 200

Discounted Fee:       INR 5999             USD 100

Batches

Spring
Summer

Autumn
Winter

Certificate

Future Career Prospects

  1. Academic Researcher: Pursue academic research in pharmaceutical sciences, focusing on taste masking, drug delivery, and computational modeling, and mentor students in related research projects.
  2. Regulatory Affairs Specialist: Assist in regulatory submissions for taste-masked pharmaceutical products, ensuring compliance with regulatory guidelines and standards.
  3. Pharmaceutical Product Manager: Manage the development, marketing, and commercialization of taste-masked pharmaceutical products, identifying market opportunities and addressing customer needs.
  4. Clinical Pharmacologist: Conduct clinical trials and studies to evaluate the safety, efficacy, and acceptability of taste-masked formulations in patient populations.
  5. Pharmaceutical Consultant: Provide consulting services to pharmaceutical companies, advising on taste masking strategies, formulation optimization, and regulatory affairs.
  6. Drug Development Project Leader: Lead interdisciplinary teams in the development of taste-masked drug products from concept to commercialization, overseeing all stages of the drug development process.

Job Opportunities

  1. Computational Chemist: Utilize computer-aided drug design (CADD) techniques to model molecular interactions between drugs and taste receptors, facilitating the rational design of taste-masked formulations.
  2. Pharmaceutical Quality Control/Assurance Specialist: Ensure the quality, safety, and efficacy of taste-masked formulations through rigorous testing, validation, and regulatory compliance.
  3. Regulatory Affairs Specialist: Assist in regulatory submissions for taste-masked pharmaceutical products, ensuring compliance with regulatory guidelines and standards.
  4. Clinical Research Scientist: Conduct clinical trials and studies to evaluate the safety, efficacy, and acceptability of taste-masked formulations in patient populations.
  5. Pharmaceutical Product Manager: Manage the development, marketing, and commercialization of taste-masked pharmaceutical products, identifying market opportunities and addressing customer needs.
  6. Academic Researcher: Pursue academic research in pharmaceutical sciences, focusing on taste masking, drug delivery, and computational modeling, and mentor students in related research projects.

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