Molecular Advances in Cancer Biology: CRISPR and Bioinformatics

Engineering the Future of Cancer Treatment: From Genes to Therapy

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MODE
Virtual (Google Meet)

TYPE
Self Paced

LEVEL
Moderate

DURATION
1 Month

About

Molecular Advances in Cancer Biology: CRISPR and Bioinformatics is an intensive one-month program designed to bridge the gap between traditional cancer biology and modern genetic editing technologies. Through a blend of theoretical knowledge and practical exercises, participants will gain a deep understanding of how genetic alterations contribute to cancer and how these can be manipulated for therapeutic strategies. The program covers the essentials of CRISPR technology, including its design, implementation, and ethical considerations, alongside hands-on training in bioinformatics tools that support data analysis and interpretation in cancer research.
As the field of genetic medicine advances, the integration of CRISPR and bioinformatics into cancer biology not only enhances our understanding of the disease but also opens new avenues for personalized medicine. This program will provide participants with the skills to contribute to cancer research and therapy development, emphasizing the translational aspect of molecular biology in clinical settings.

Aim

This program aims to equip participants with cutting-edge knowledge and practical skills in CRISPR technology and bioinformatics, focusing on their applications in cancer biology. Students will explore the molecular mechanisms of cancer, learn to manipulate genes using CRISPR, and analyze biological data, paving the way for innovations in cancer treatment and research.

Program Objectives

Understand the biological basis of cancer and the role of genes in oncogenesis.
Learn the fundamentals of CRISPR technology and its application in gene editing.
Apply bioinformatics tools to analyze and interpret genetic data related to cancer.
Evaluate the ethical, legal, and social implications of using CRISPR in cancer research.
Develop practical skills in designing CRISPR experiments and conducting bioinformatic analysis.

Program Structure

Week 1: Introduction to Cancer Biology and CRISPR Technology

Overview of Cancer Biology: Understanding the cellular and molecular foundations of cancer.
Introduction to CRISPR-Cas9: Exploring the mechanics of CRISPR technology and its revolutionary impact.
Bioinformatics in Cancer Research: Introduction to the bioinformatics tools used in genomic studies.
Designing CRISPR Experiments: Principles of guide RNA design and target selection.

Week 2: CRISPR Applications in Cancer Research

CRISPR for Oncogene Targeting: Strategies for using CRISPR to inactivate oncogenes.
Tumor Suppressor Genes and CRISPR: Enhancing the expression of tumor suppressor genes using CRISPR.
Bioinformatics for CRISPR Data Analysis: Tools and techniques for analyzing CRISPR editing results.
Ethical Considerations in Gene Editing: Discuss the ethical implications of using CRISPR in cancer therapy.

Week 3: Advanced Bioinformatics Techniques

Sequencing Technologies in Cancer: Overview of Next-Generation Sequencing (NGS) technologies.
Data Management and Analysis: Handling and analyzing large datasets from genomic studies.
Integrative Genomics: Combining data from various sources to understand cancer pathways.
Machine Learning in Genomics: Applying AI and machine learning to predict cancer progression.

Week 4: Translational Applications and Future of CRISPR

CRISPR in Clinical Trials: Current status of CRISPR-based therapies in clinical trials.
Personalized Medicine and CRISPR: Customizing cancer treatment based on genetic profiles.
Future Technologies in Gene Editing: Exploring new CRISPR systems and potential improvements.
Preparing for Real-World Applications: How to move from research to real-world applications.

Participant’s Eligibility

Undergraduate degree in Biology, Genetics, Biotechnology, or related fields.
Professionals working in biomedical, biotechnological, and pharmaceutical sectors.
Researchers and academics with an interest in genetic engineering and cancer research.

Program Outcomes

Mastery of CRISPR and its applications in cancer research.
Proficient use of bioinformatics tools for genetic data analysis.
Ability to design and interpret genetic experiments.
Understanding of ethical considerations in genetic research.
Preparedness for advanced research or professional roles in genetic medicine.

Fee Structure

Standard Fee: INR ~~11,998~~ USD ~~240~~

Discounted Fee: INR 5999 USD 120

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Certificate

Program Assessment

Certification to this program will be based on the evaluation of following assignment (s)/ examinations:

Exam	Weightage
Mid Term Assignments	20 %
Final Online Exam	30 %
Project Report Submission (Includes Mandatory Paper Publication)	50 %

To study the printed/online course material, submit and clear, the mid term assignments, project work/research study (in completion of project work/research study, a final report must be submitted) and the online examination, you are allotted a 1-month period. You will be awarded a certificate, only after successful completion/ and clearance of all the aforesaid assignment(s) and examinations.