Epigenome Editing: Modifying Gene Expression Without Changing DNA

Unlock the Power of Epigenome Editing to Control Gene Expression Without Changing DNA

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MODE
Online/ e-LMS

TYPE
Self Paced

LEVEL
Moderate

DURATION
1 Month

About

Epigenome editing is revolutionizing our understanding of gene regulation by enabling precise control over gene expression without making permanent changes to the DNA sequence. This 1-month program covers the fundamentals of epigenetic mechanisms, such as DNA methylation and histone modification, and explores how targeted epigenome editing can be used to modulate these processes. Participants will gain insights into the latest tools, such as CRISPR-based epigenetic modifiers, and their applications in research and disease treatment.
The program emphasizes real-world applications, including using epigenome editing to study gene function, treat genetic disorders, and develop new therapeutic approaches for diseases like cancer and neurological disorders.

Aim

This program aims to introduce participants to the cutting-edge field of epigenome editing, which allows the modification of gene expression without altering the underlying DNA sequence. The program will explore the tools, techniques, and applications of epigenome editing in fields like biomedical research, therapeutics, and personalized medicine.

Program Objectives

Understand the fundamentals of epigenetics and gene regulation.
Learn about various tools used for epigenome editing, including CRISPR-based technologies.
Explore the therapeutic potential of epigenome editing in disease treatment.
Design and analyze epigenome editing experiments.
Evaluate the ethical and regulatory aspects of epigenetic modifications.

Program Structure

Week 1: Introduction to Epigenetics and Gene Regulation

Overview of Epigenetics: DNA Methylation, Histone Modification, and Non-coding RNA.
Gene Regulation Mechanisms: Understanding Transcriptional Control.
Introduction to Epigenome Editing Tools: CRISPR-dCas9 and Other Technologies.
Applications of Epigenome Editing in Biomedical Research.

Week 2: Epigenome Editing Techniques and Tools

CRISPR-dCas9 in Epigenome Editing: Mechanisms and Applications.
Design and Development of Epigenetic Modifiers.
Tools for Targeted DNA Methylation and Histone Modification.
Case Studies: Real-World Applications of Epigenome Editing in Research.

Week 3: Therapeutic Applications of Epigenome Editing

Epigenetic Therapies for Cancer: Targeting Aberrant Gene Expression.
Treating Neurological Disorders Using Epigenome Editing.
Personalized Medicine: Tailoring Therapies through Epigenetic Modulation.
Bioinformatics for Epigenetic Data Analysis: Tools and Techniques.

Week 4: Ethical, Regulatory, and Future Directions in Epigenome Editing

Ethical Considerations in Epigenome Editing: Balancing Innovation and Responsibility.
Regulatory Challenges and Compliance in Epigenetic Research.
Emerging Technologies in Epigenome Editing: Beyond CRISPR.
Career Opportunities in Epigenetics and Gene Therapy.

Participant’s Eligibility

Undergraduate degree in Molecular Biology, Biotechnology, or related fields.
Professionals in biomedical research or genetic engineering.
Individuals with a strong interest in gene regulation and therapeutic development

Program Outcomes

Mastery of epigenetic mechanisms and their role in gene regulation.
Ability to design epigenome editing experiments using state-of-the-art tools.
Knowledge of therapeutic applications of epigenome editing.
Understanding of bioinformatics tools for analyzing epigenetic data.
Awareness of ethical and regulatory considerations in epigenetic research.

Fee Structure

Standard Fee: INR ~~4,998~~ USD ~~110~~

Discounted Fee: INR 2499 USD 55

We are excited to announce that we now accept payments in over 20 global currencies, in addition to USD. Check out our list to see if your preferred currency is supported. Enjoy the convenience and flexibility of paying in your local currency!

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Key Takeaways

Program Assessment

Certification to this program will be based on the evaluation of following assignment (s)/ examinations:

Exam	Weightage
Mid Term Assignments	50 %
Project Report Submission (Includes Mandatory Paper Publication)	50 %

To study the printed/online course material, submit and clear, the mid term assignments, project work/research study (in completion of project work/research study, a final report must be submitted) and the online examination, you are allotted a 1-month period. You will be awarded a certificate, only after successful completion/ and clearance of all the aforesaid assignment(s) and examinations.