Self Paced

Comet Assay to Study Antimutagenic Activity of Different Compounds

Decoding DNA Protection: Explore the Power of Antimutagenic Compounds

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Online/ e-LMS
Self Paced
1 Months


The “Comet Assay to Study Antimutagenic Activity of Different Compounds” program is designed to provide a deep dive into the comet assay (single cell gel electrophoresis), a versatile and sensitive technique for measuring DNA damage and repair. Participants will learn the foundational principles and step-by-step methodologies of conducting comet assays, as well as how to interpret and utilize the results in practical and research settings.


This program aims to equip participants with the skills to conduct comet assays to evaluate the antimutagenic properties of various compounds. It focuses on understanding the interaction between these compounds and DNA, methods to mitigate genetic damage, and the implications for cancer research and environmental science.

Program Objectives

  • Master the comet assay technique for detecting DNA damage.
  • Understand the principles of antimutagenic activity and its measurement.
  • Develop skills to analyze and interpret assay data effectively.
  • Explore the use of comet assay in various applied sciences including toxicology and pharmacology.
  • Learn about current trends and future directions in genetic damage prevention.

Program Structure

Modues 1: Introduction to Comet Assay

What is Comet Assay?

Applications of Comet Assay

The Principle of Comet Assay

Why is Comet Assay important?

Theoretical background of Comet Assay

  • Protocol for Performing Comet Assay
  • Sample preparation
  • Electrophoresis
  • Visualization and analysis of DNA damage
  • Q&A Session  
  • Session 2: Analysis of Results of Comet Assay
  • Interpretation of Comet Assay data
  • Quantification of DNA damage
  • Uses of Comet Assay
  • How Comet Assay is used in toxicology and genotoxicity studies
  • Future applications of Comet Assay
  • Modifications or Improvisations of Comet Assay
  • Various modifications and improvements to the original Comet Assay protocol
  • Advantages and limitations of different modifications
  • Q&A Session

Participant’s Eligibility

  • Undergraduate degree in Biology, Biochemistry, Environmental Science, or related fields.
  • Professionals in pharmaceutical, biotechnology, or environmental sectors.
  • Individuals with an interest in genetic research and its applications in health and safety.

Program Outcomes

  • Proficiency in performing comet assays
  • Knowledge of genetic damage mechanisms and repair
  • Skills in data collection and interpretation
  • Understanding of compound interactions with DNA
  • Preparation for roles in genetic and environmental health research

Fee Structure

Standard Fee:           INR 4,998           USD 110

Discounted Fee:       INR 2499             USD 55





Program Assessment

Certification to this program will be based on the evaluation of following assignment (s)/ examinations:

Exam Weightage
Mid Term Assignments 20 %
Final Online Exam 30 %
Project Report Submission (Includes Mandatory Paper Publication) 50 %

To study the printed/online course material, submit and clear, the mid term assignments, project work/research study (in completion of project work/research study, a final report must be submitted) and the online examination, you are allotted a 1-month period. You will be awarded a certificate, only after successful completion/ and clearance of all the aforesaid assignment(s) and examinations.

Program Deliverables

  • Access to e-LMS
  • Real Time Project for Dissertation
  • Project Guidance
  • Paper Publication Opportunity
  • Self Assessment
  • Final Examination
  • e-Certification
  • e-Marksheet

Future Career Prospects

  • Genetic Research Scientist
  • Environmental Health Specialist
  • Pharmaceutical Researcher
  • Academic in Molecular Biology
  • Lab Technician specializing in genetic assays
  • Regulatory Affairs Coordinator

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