
Analysis of Microarray Data using Machine Learning/AI in R
Decoding Genetic Data: AI-Powered Microarray Analysis in R.
Skills you will gain:
About Program:
Microarrays are one of the most common tools to understand biological spectacle by large-scale dimensions of biological samples, typically DNA, RNA, or proteins. The technique has been used for a variety of purposes in life science research, ranging from gene expression profiling to SNP or other biomarker identification, and further, to understand relations between genes and their activities on a large scale. Artificial intelligence (AI) and machine learning (ML) techniques can be used to analyse microarray data to gain insights into biological processes. Machine learning tools can automate the analysis of microarray data to identify patterns of gene expression. These patterns can be used to compare gene expression between different conditions, such as healthy and diseased cells. There are no curated machine learning/AI-ready datasets that meet the requirements for machine learning analyses within public functional genomics repositories at the moment.
The R language supports identifying gene expression through Bioconductor packages to show all differential gene expressions by generating the volcano map, Euclidean distances to perform clustering, Venn diagram, and heatmap.
Aim: The aim of microarray data analyses is the identification of genes showing significant differences in expression levels between two or more groups.
Program Objectives:
- Master the fundamentals of microarray technology and its applications.
- Utilize R to preprocess, analyze, and interpret microarray data.
- Apply AI and machine learning techniques to uncover patterns in complex genetic datasets.
- Develop skills in statistical analysis and biomarker identification.
- Understand the ethical implications of genomic data handling and reporting.
What you will learn?
DAY 1: Functional genomics repositories
- General Overview of public genomics repositories
- Overview of GEO2R, procedure to use, Edit options and features, Limitations and caveats, Summary Statistics.
DAY 2: R studio and Bioconductor packages
- R and Bioconductor packages installation
- GEOquery and limma Bioconductor package
DAY 3: Microarray Data Analysis
- Gene expression analysis with GEOquery and limma for Microarray data analysis
Mentor Profile
Fee Plan
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Intended For :
- Undergraduate degree in Bioinformatics, Genomics, Computational Biology, or related fields.
- Professionals in biotechnological, pharmaceutical sectors, or clinical research.
- Individuals with foundational knowledge of molecular biology and an enthusiasm for computational data analysis.
Career Supporting Skills
Program Outcomes
- Proficiency in analyzing microarray data using advanced AI and machine learning techniques
- Capable of contributing to genetic research, diagnostics, and therapeutic developments
