Aim
NANOmedX: Future of Drug Delivery trains participants to understand and design next-generation drug delivery systems using nanomedicine principles—from material selection and formulation to targeting strategies, characterization, and translational thinking. You will learn how nano-enabled carriers improve stability, biodistribution, controlled release, and therapeutic index, while also understanding safety, manufacturing, and regulatory fundamentals.
Program Objectives
- Understand Modern Drug Delivery: Why conventional delivery fails and how nanocarriers solve key limitations.
- Learn Nanocarrier Platforms: Liposomes, polymeric nanoparticles, micelles, dendrimers, SLNs/NLCs, and inorganic systems.
- Targeting & Release Design: Passive vs active targeting, stimuli-responsive release, and controlled delivery strategies.
- Formulation Know-How: Encapsulation, loading, stability, surface functionalization, and scale-up considerations.
- Characterization Skills: Size, charge, morphology, release kinetics, and basic in vitro performance testing.
- Safety & Translation: Toxicity basics, immunogenicity, biodistribution, quality-by-design, and regulatory overview.
- Hands-on Application: Build a capstone nanomedicine delivery concept with a complete design rationale.
Program Structure
Module 1: Why the Future Needs Smarter Drug Delivery
- Limitations of conventional dosage forms: instability, off-target toxicity, low bioavailability.
- Drug delivery goals: enhance efficacy, reduce side effects, improve patient compliance.
- Biological barriers: mucus, cell membranes, RES clearance, BBB (conceptual).
- Where nanomedicine fits: precision delivery, controlled release, and combination therapies.
Module 2: Nanomedicine Fundamentals for Drug Delivery
- Core concepts: size effects, surface chemistry, corona formation, and interaction with biology.
- Key design parameters: size, PDI, zeta potential, hydrophobicity, ligand density.
- Drug properties vs carrier choice: solubility, stability, permeability, and dose constraints.
- Formulation strategy map: from therapeutic objective to carrier platform selection.
Module 3: Nanocarrier Platforms (What to Use and When)
- Lipid systems: liposomes, SLNs, NLCs—advantages and use cases.
- Polymer systems: PLGA-type concepts, polymeric NPs, micelles, nanogels.
- Dendrimers and supramolecular carriers (intro-level).
- Inorganic and hybrid systems: silica, gold, iron oxide (conceptual + safety considerations).
Module 4: Loading, Encapsulation & Stability Design
- Encapsulation approaches: physical entrapment, adsorption, conjugation (concepts).
- Drug loading vs encapsulation efficiency—how to interpret results.
- Stability: aggregation, leakage, oxidation/hydrolysis; storage and lyophilization basics.
- Surface modification: PEGylation concepts, charge tuning, ligand attachment.
Module 5: Targeting Strategies & Triggered Release
- Passive targeting: EPR effect and its real-world constraints (balanced view).
- Active targeting: antibodies, peptides, aptamers, small-molecule ligands.
- Stimuli-responsive delivery: pH, enzymes, redox, temperature, light, magnetic triggers.
- Designing release profiles: burst vs sustained release and application matching.
Module 6: Characterization Toolkit for Nanomedicine
- Size and distribution: DLS concepts, PDI interpretation, common artifacts.
- Surface charge: zeta potential meaning and limitations.
- Morphology: TEM/SEM basics; when imaging is necessary.
- Drug release kinetics and data interpretation; basic fitting concepts (intro).
Module 7: Biological Evaluation (In Vitro to In Vivo Thinking)
- Cell uptake and trafficking concepts; endosomal escape basics.
- Biocompatibility and cytotoxicity screening: what tests show (and don’t show).
- Protein corona, immune recognition, and clearance pathways (conceptual).
- Translational challenges: biodistribution, PK/PD, and dosage form constraints.
Module 8: Manufacturing, Scale-Up, Quality & Regulatory Basics
- Scale-up realities: reproducibility, batch variability, sterility, and stability.
- Quality-by-Design (QbD) mindset for formulation development (intro).
- CMC basics: critical quality attributes (CQAs) and critical process parameters (CPPs).
- Regulatory overview: safety packages, characterization expectations, and documentation.
Final Project
- Design a nano-enabled drug delivery strategy for a chosen indication (cancer, infection, CNS, inflammation, etc.).
- Select the carrier platform and justify based on drug + biological barrier constraints.
- Define targeting/release approach, characterization plan, and safety considerations.
- Deliverables: concept note + formulation plan + characterization checklist + risk/translation notes.
Participant Eligibility
- Students and professionals in Biotechnology, Pharmacy, Nanotechnology, Biomedical Engineering, Chemistry, Materials Science
- Researchers working in formulation, drug delivery, cancer biology, infectious diseases, or biomaterials
- R&D professionals in pharma/biotech seeking a structured understanding of nanomedicine delivery systems
- Anyone with a life-science background aiming to enter nanomedicine and advanced therapeutics
Program Outcomes
- Platform Understanding: Ability to select suitable nanocarrier types for specific drugs and use cases.
- Design Thinking: Confidence in designing targeting and release strategies with realistic constraints.
- Characterization Literacy: Ability to interpret common nanomedicine characterization results correctly.
- Translation Awareness: Understanding of safety, scale-up, and regulatory expectations at a foundation level.
- Portfolio Deliverable: A capstone nanomedicine design proposal that you can showcase.
Program Deliverables
- Access to e-LMS: Full access to course materials, templates, and reference readings.
- Nanomedicine Toolkit Pack: Carrier selection matrix, loading/release planning sheets, characterization checklist.
- Case Studies: Nano-delivery examples (lipid/polymer/inorganic) and design trade-offs.
- Hands-on Project Support: Guided capstone review and feedback.
- Final Assessment: Certification after assignments + capstone submission.
- e-Certification and e-Marksheet: Digital credentials provided upon successful completion.
Future Career Prospects
- Nanomedicine / Drug Delivery Research Associate
- Formulation Scientist (Nano-formulations)
- Drug Product Development Associate
- Translational Nanotechnology Associate
- Regulatory/CMC Support Associate (Nanomedicine)
Job Opportunities
- Pharma & Biotech Companies: Advanced formulation, targeted therapeutics, delivery platform R&D.
- CDMOs & Formulation Labs: Nano-formulation development, optimization, characterization, tech transfer.
- Academic & Research Institutes: Nanomedicine design, biomaterials research, translational programs.
- Hospitals & Clinical Research Teams: Translational evaluation support (non-clinical R&D roles).
- HealthTech Startups: Rapid prototyping of delivery systems and proof-of-concept studies.









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