Program Structure

Module 1: Introduction to Bio-Nanopharmaceuticals

• What are bio-nanopharmaceuticals and why they are important in the modern pharmaceutical landscape.
• Overview of nanotechnology and its applications in drug delivery systems, therapeutic use, and drug design.
• Nanopharmaceuticals in improving bioavailability and targeted drug delivery.

Module 2: Nanoparticles and Nanocarriers in Drug Delivery

• Types of nanocarriers: Liposomes, polymeric nanoparticles, micelles, dendrimers, and solid lipid nanoparticles.
• Principles of drug encapsulation and release mechanisms: passive vs active targeting.
• Advantages of nanoparticles in overcoming drug resistance, improving half-life, and controlling drug release.

Module 3: Nanopharmaceuticals in Cancer Therapy

• Role of nanotechnology in targeting cancer cells and enhancing therapeutic efficacy.
• Nanoparticle-based drug delivery in overcoming challenges in cancer therapy, such as tumor heterogeneity and drug resistance.
• Examples of nanopharmaceuticals used in chemotherapy, immunotherapy, and gene therapy.

Module 4: Gene Delivery Using Bio-Nanopharmaceuticals

• How nanoparticles are used for gene delivery: DNA, RNA, and CRISPR-based therapies.
• Challenges in gene therapy: delivery efficiency, immune response, and targeting specificity.
• Examples of gene delivery systems and the future potential of bio-nanopharmaceuticals in gene therapies.

Module 5: Bio-Nanopharmaceuticals in Personalized Medicine

• Exploring how nanotechnology allows for personalized drug delivery based on patient-specific needs.
• Role of nanoparticles in tailoring drug doses, treatment schedules, and reducing side effects.
• Emerging trends in personalized medicine and how bio-nanopharmaceuticals are transforming treatments for chronic diseases.

Module 6: Regulatory and Ethical Considerations in Bio-Nanopharmaceuticals

• Overview of regulatory frameworks for bio-nanopharmaceuticals (FDA, EMA, etc.).
• Ethical concerns in developing nano-based drug delivery systems, including long-term safety, bioaccumulation, and toxicology.
• Challenges in moving from preclinical studies to clinical trials for bio-nanopharmaceutical products.

Module 7: Challenges in Manufacturing and Scaling-Up Bio-Nanopharmaceuticals

• Challenges in scaling up the production of carbon nanomaterials from kitchen waste for industrial use.
• Manufacturing methods: from lab scale to industrial scale.
• Ensuring consistency, quality control, and good manufacturing practices (GMP) for bio-nanopharmaceuticals.

Module 8: Future Trends and Innovations in Bio-Nanopharmaceuticals

• Exploring the future potential of nanopharmaceuticals in precision medicine, vaccines, and advanced drug delivery systems.
• Emerging innovations: smart drug delivery, self-healing nanoparticles, and multifunctional nanomaterials.
• The future of bio-nanopharmaceuticals in addressing global health challenges like cancer, infectious diseases, and aging.

Final Project

• Design and develop a bio-nanopharmaceutical for a specific disease target, incorporating the principles learned in the course.
• Synthesize and characterize nanoparticles, and evaluate their drug delivery efficiency and targeting specificity.
• Example projects: Develop a nanoparticle-based chemotherapy delivery system or a gene delivery nanoparticle for targeted treatment.