AED
UAD Dirham
Code: AED
Industrial Program
Molecular Basis of Cancer: Therapeutics and Targets
Unraveling cancer’s secrets: Design smarter therapies for a brighter future.
Early access to the e-LMS platform is included
About This Course
This program delves into the intricate world of the molecular basis of cancer. Through a combination of lectures, discussions, and case studies, participants will gain a deeper understanding of the cellular and molecular underpinnings of cancer, and how these insights are translated into targeted therapeutic approaches.
Aim
To equip participants with a comprehensive understanding of the molecular mechanisms underlying cancer and explore the development of targeted therapies based on these insights.
Program Objectives
- Explore the hallmarks of cancer and their molecular basis.
- Analyze different types of mutations and their role in cancer initiation and progression.
- Understand the principles of targeted cancer therapy.
- Discuss the latest advancements in targeted therapies (e.g., small molecules, antibodies, immunotherapies).
- Analyze the challenges associated with drug resistance and treatment optimization.
- Explore emerging therapeutic strategies for personalized cancer medicine.
Program Structure
Month 1: Molecular Oncology — Foundations and Pathways
Week 1: Introduction to Cancer Biology
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Hallmarks of cancer
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Genetic and epigenetic changes
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Genomic instability and mutation types
Week 2: Oncogenes and Tumor Suppressors
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Proto-oncogenes vs. oncogenes
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p53, Rb, and other key tumor suppressors
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Loss-of-function vs. gain-of-function mutations
Week 3: Signal Transduction in Cancer
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PI3K/Akt, MAPK, Wnt, JAK/STAT pathways
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Cross-talk and feedback mechanisms
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Growth factor receptors and receptor tyrosine kinases
Week 4: Tumor Microenvironment & Cancer Stem Cells
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Role of fibroblasts, immune cells, and angiogenesis
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Invasion, metastasis, EMT
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Cancer stem cells and therapy resistance
Month 2: Diagnostic Platforms and Target Discovery
Week 5: Molecular Diagnostics and Biomarkers
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PCR, qPCR, RT-PCR, FISH, IHC
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Biomarker validation and clinical utility
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Tumor heterogeneity and clonal evolution
Week 6: Genomics and Precision Profiling
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NGS technologies and exome sequencing
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Mutation databases (COSMIC, TCGA)
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Companion diagnostics and precision treatment plans
Week 7: Targeted Cancer Therapeutics
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Monoclonal antibodies, tyrosine kinase inhibitors
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Hormone therapy and CDK inhibitors
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Resistance mechanisms and secondary mutations
Week 8: RNA-based and Gene Therapies
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Antisense oligos, siRNA, miRNA therapeutics
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CRISPR-Cas in cancer gene editing
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Case studies: BRCA, EGFR, KRAS targeting
Month 3: Advanced Therapeutics and Translational Oncology
Week 9: Immunotherapies and Immune Checkpoint Inhibition
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PD-1/PD-L1, CTLA-4, CAR-T therapies
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Neoantigens and T-cell reprogramming
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Immune-related adverse events (irAEs)
Week 10: Nanotechnology and Drug Delivery
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Nanocarriers, liposomes, and polymer-based systems
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Tumor targeting and controlled release strategies
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Deep tech platforms for real-time monitoring
Week 11: Clinical Trials and Regulatory Frameworks
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Trial design: Phase I–IV
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Ethics, consent, and protocol standardization
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Regulatory agencies: FDA, EMA, CDSCO
Week 12: Future Directions in Cancer Therapeutics
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AI in drug discovery and predictive modeling
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Organoids, lab-on-chip, and digital twin models
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Roadmap to translational research and biotech innovation
Who Should Enrol?
- Biotech, Pharma, and Life Sciences graduates
- Post-graduates with a focus on oncology, cell biology, or molecular biology
- Academicians researching cancer biology or therapeutics
- Industry professionals seeking to update their knowledge in cancer research and drug development
- Anyone interested in the molecular basis of cancer and the development of novel therapies.
Program Outcomes
- Acquire a strong foundation in the molecular mechanisms driving cancer development.
- Gain insights into the rationale behind targeted therapies for various cancers.
- Develop an understanding of the challenges and opportunities in cancer therapeutics.
- Identify potential career paths within the field of cancer research and drug discovery.
Fee Structure
Standard: ₹14,998 | $258
Discounted: ₹7499 | $129
We accept 20+ global currencies. View list →
What You’ll Gain
- Full access to e-LMS
- Real-world dry lab projects
- One-on-one project guidance
- Publication opportunity
- Self-assessment & final exam
- e-Certificate & e-Marksheet
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Centre of Excellence
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Networking & Learning
Connect with global researchers and mentors.
Global Recognition
Worth ₹20,000 / $1,000 in academic value.
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