Genome Editing Technologies: Principles and Applications
Genome Editing Technologies,Pros and Cons
Early access to e-LMS included
About This Course
The “Genome Editing Technologies: Principles and Applications” program offers a comprehensive exploration of the tools and methods used to modify genetic material. Throughout this one-month intensive program, participants will delve into the science behind genome editing, including CRISPR, TALENs, and ZFNs, and their applications in treating genetic disorders, enhancing agricultural productivity, and developing new therapeutic approaches.
Aim
This program is designed to equip participants with a robust understanding of genome editing technologies and their transformative impact across various sectors. By exploring both the principles and diverse applications of these technologies, students will be prepared to lead and innovate in the dynamic fields of genetics, agriculture, and medicine.
Program Objectives
- Master the foundational principles of genome editing technologies.
- Apply genome editing tools in various biological and medical contexts.
- Evaluate the ethical, legal, and social issues associated with genome editing.
- Develop critical thinking and problem-solving skills in genetic manipulation.
- Prepare for advanced research or career opportunities in genetic technologies.
Program Structure
Week 1: Fundamentals of Genome Editing Technologies
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Introduction to gene structure and regulation
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Evolution of genome editing: ZFNs, TALENs, CRISPR
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Mechanisms of site-specific DNA cleavage and repair
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NHEJ vs HDR: pathway selection and outcomes
Week 2: CRISPR and Beyond – Mechanisms and Toolkits
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CRISPR-Cas9 and its variants (Cas12, Cas13)
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Guide RNA design and PAM sequence specificity
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Base editing and prime editing technologies
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Multiplexing and epigenome editing capabilities
Week 3: Applications in Health, Agriculture, and Research
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Functional genomics and gene knockout models
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Therapeutic genome editing for monogenic diseases
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Agricultural trait enhancement and biotic stress tolerance
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Case studies: Sickle Cell Disease, muscular dystrophy, rice yield improvement
Week 4: Delivery Methods, Ethics, and Future Outlook
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Viral and non-viral delivery strategies (LNPs, electroporation)
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AI and computational tools in target prediction and off-target screening
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Regulatory frameworks and bioethical concerns
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Future prospects: synthetic biology, in vivo editing, germline modifications
Who Should Enrol?
- Undergraduate degree in Biotechnology, Genetics, or related fields.
- Professionals in the biomedical, agricultural, or pharmaceutical industries.
- Individuals with a strong foundation in molecular biology and a passion for innovative technologies.
Program Outcomes
- Comprehensive understanding of genome editing mechanisms and tools
- Ability to design and conduct experiments using genome editing technologies
- Insights into the ethical, social, and regulatory dimensions of genetic editing
- Skills to innovate in fields of genetics and biotechnology
- Preparation for careers or advanced studies in genetic technologies
Fee Structure
Standard: ₹4,998 | $110
Discounted: ₹2499 | $55
We accept 20+ global currencies. View list →
What You’ll Gain
- Full access to e-LMS
- Real-world dry lab projects
- 1:1 project guidance
- Publication opportunity
- Self-assessment & final exam
- e-Certificate & e-Marksheet
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