Aim
Biomedical Innovations through Bionanotechnology: Exploring Medical Applications explains how nanoscale platforms enable advanced diagnostics, targeted therapies, imaging, antimicrobial solutions, and regenerative medicine. Learn design principles, characterization, safety basics, and translation pathways.
Program Objectives
- Core Concepts: nano–bio interactions, surface chemistry, targeting basics.
- Diagnostics: nanosensors, point-of-care testing, biomarkers (overview).
- Imaging: nano-contrast agents and theranostics concepts.
- Drug Delivery: nano-carriers, controlled release, tissue targeting.
- Antimicrobials: nanoantibiotics, biofilms, coatings (overview).
- Regeneration: scaffolds, hydrogels, wound healing concepts.
- Safety: biocompatibility, toxicity, biodistribution concepts.
- Capstone: design a bionano solution for a medical need.
Program Structure
Module 1: Foundations of Bionanotechnology
- Why nanoscale matters in biology and medicine.
- Protein corona, immune interaction, and stability concepts.
- Common platforms: liposomes, LNPs, polymer NPs, metal/oxide NPs (overview).
- Design goals: specificity, safety, reproducibility.
Module 2: Nano-Enabled Diagnostics
- Biosensing principles: recognition and signal generation (overview).
- Electrochemical and optical nanosensors (intro).
- Point-of-care platforms and rapid testing concepts.
- Performance metrics: sensitivity, specificity, LoD (intro).
Module 3: Imaging and Theranostics
- Nanoparticles for imaging: contrast enhancement concepts.
- Targeted imaging and multiplex detection (overview).
- Theranostics: combining imaging + therapy (intro).
- Design constraints: dose, stability, clearance.
Module 4: Targeted Drug Delivery Systems
- Delivery barriers and how nanocarriers help.
- Passive vs active targeting; ligand concepts.
- Controlled release: sustained and stimuli-responsive (overview).
- Case examples: oncology, inflammation, infections (overview).
Module 5: Nano-Based Antimicrobials and Biofilm Control
- Nanoantibiotics and antimicrobial mechanisms (overview).
- Anti-biofilm coatings and surface engineering.
- Wound dressings with nano-enabled action (overview).
- Resistance and safety considerations.
Module 6: Regenerative Medicine and Tissue Engineering
- Scaffolds, nanofibers, hydrogels (overview).
- Cell–material interactions and biocompatibility concepts.
- Growth factor delivery and wound healing systems (intro).
- 3D printing and advanced biomaterials (intro).
Module 7: Characterization and Safety Testing
- Characterization: size/PDI, zeta, morphology, stability.
- Bio-testing: cytotoxicity, hemocompatibility, uptake assays (overview).
- Biodistribution and clearance concepts.
- Risk controls and safety-by-design basics.
Module 8: Translation to Product
- Scale-up, batch consistency, and quality concepts.
- Documentation: SOPs, specs, study reports (overview).
- Regulatory and ethics basics (research/clinical research context).
- Market fit and clinical adoption considerations.
Final Project
- Select a medical problem (diagnosis, therapy, antimicrobial, or regeneration).
- Deliverables: platform choice + design rationale + test plan + safety checklist + short report.
- Submit: biomedical innovation dossier.
Participant Eligibility
- Students/professionals in Biotechnology, Biomedical Engineering, Pharmacy, Nanotechnology
- Researchers in biomaterials, drug delivery, diagnostics
- Basic biology and chemistry helpful
Program Outcomes
- Understand bionanotechnology platforms and medical use cases.
- Plan design, characterization, and safety workflows.
- Evaluate feasibility for translation and scale-up basics.
- Create a portfolio-ready bionanotechnology project.
Program Deliverables
- e-LMS Access: lessons, templates.
- Toolkit: platform selection sheet, testing checklist, report outline.
- Assessment: certification after submission.
- e-Certification and e-Marksheet: digital credentials.
Future Career Prospects
- Bionanotechnology Research Associate
- Nanomedicine Analyst (Entry-level)
- Biomedical R&D Associate
- Diagnostics Product Trainee
Job Opportunities
- Biotech/Pharma: nanomedicine and drug delivery R&D.
- Diagnostics: biosensors and point-of-care development teams.
- Medical Devices: antimicrobial coatings and wound care products.
- Universities: translational nanotechnology and biomaterials labs.
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