A Hands-On Course for Genome Data Analysis

About

This one-month intensive program is designed to provide participants with a thorough introduction to genomic data analysis. Through interactive sessions, attendees will learn how to access genomic databases, retrieve relevant data, and utilize bioinformatics tools for analysis. Participants will engage in practical exercises to analyze real-world genomic datasets, enhancing their understanding of the data’s implications in biological research and medical applications.

The program emphasizes a hands-on approach, allowing participants to work with tools like NCBI and UCSC Genome Browser, making the learning experience both engaging and applicable. By the end of the day, attendees will have gained valuable insights into the methodologies used in genomic research, preparing them for further exploration in the field of bioinformatics.

Aim

This program aims to equip participants with practical skills in genomic data analysis through hands-on experience using popular bioinformatics tools. Participants will explore genomic data retrieval, analysis, and visualization, enabling them to understand the underlying biological significance of genomic sequences.

Program Objectives

• To understand the basics of genomic data and its significance.
• To gain proficiency in using bioinformatics tools for data analysis.
• To analyze genomic datasets using practical techniques.
• To visualize and interpret genomic data effectively.
• To enhance problem-solving skills in genomic research scenarios.

Program Structure

Introduction to Bioinformatics

Overview of bioinformatics and its applications in genomics.

Getting Started with Free Tools

Overview of free bioinformatics tools and resources. Introduction to platforms such as:

• NCBI for accessing genomic data.
• UCSC Genome Browser for visualizing genomic data.
• Galaxy for data analysis workflows.

Hands-On Session 1: Accessing and Retrieving Genomic Data

• Activity: Participants will use the NCBI database to search for a specific gene and download its genomic sequence in FASTA format.
• Tools: NCBI Gene database and FASTA file handling.

Hands-On Session 2: Sequence Analysis Using Bioinformatics Tools

• Activity: Participants will analyze the downloaded sequence using tools like MEGA X for phylogenetic analysis (if needed, this can be replaced with online tools) and BLAST for sequence alignment and finding similar sequences.
• Tools: NCBI BLAST.

Hands-On Session 3: Visualizing Genomic Data

• Activity: Participants will upload their sequences to the UCSC Genome Browser to visualize gene structure and annotations.
• Tools: UCSC Genome Browser.

Case Study: Analyzing a Gene of Interest

Participants will choose a gene of interest, perform a simple analysis, and document their findings. Discussion on how to interpret results and the biological significance of findings.

Participant’s Eligibility

• Undergraduate degree in Biology, Bioinformatics, Computer Science, or related fields.
• Professionals in healthcare, research, or related industries.
• Individuals with a strong interest in genetics and data analysis.

Program Outcomes

• Enhanced understanding of genomic data analysis techniques.
• Practical experience with bioinformatics tools.
• Improved data visualization and interpretation skills.
• Familiarity with current trends in genomics research.
• A foundational knowledge base for further studies in bioinformatics.

Program Deliverables

• Access to e-LMS
• Real Time Project for Dissertation
• Project Guidance
• Paper Publication Opportunity
• Self Assessment
• Final Examination
• e-Certification
• e-Marksheet