Quantum dots (QDs) are nanoscale semiconductor particles with unique optical and electronic properties that make them valuable for a variety of applications, including fluorescence imaging. In fluorescence imaging, QDs are used as fluorescent probes for a range of biological applications, such as in vitro cell imaging, in vivo imaging, and molecular biology. This article provides an overview of the recent advancements in QD-based fluorescence imaging and discusses the benefits and limitations of QDs compared to traditional fluorescent probes.

Important Publications:

  1. “Quantum dots for in vitro and in vivo biological imaging” by Xiaoyuan Chen and Shuang Wang, Nature Biotechnology (2007).
  2. “Quantum dot bioconjugates for imaging, labelling and sensing” by Haifeng Gao, Nature Materials (2008).
  3. “Quantum dot-based cellular imaging: opportunities and challenges” by Chenjie Xu and Shuming Nie, Nature Reviews Materials (2017).


  1. K. E. Murphy, S. J. Oldenburg, N. J. Halas, J. K. West, “Quantum dots for live cells, in vitro and in vivo imaging,” Nature Biotechnology, vol. 21, no. 11, pp. 1369-1376, 2003.
  2. L. Zhang, X. Wang, W. Fan, J. Guo, Z. Zhang, “Quantum dots for in vitro and in vivo biological labeling and imaging,” Journal of Biomedical Nanotechnology, vol. 6, no. 1, pp. 1-18, 2010.
  3. X. Chen, S. Wang, “Quantum dots for in vitro and in vivo biological imaging,” Nature Biotechnology, vol. 25, no. 2, pp. 317-327, 2007.

Keywords: fluorescence imaging, quantum dots, biological applications, in vitro, in vivo, molecular biology

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