Advanced Workshop on CAR-T Therapy: Oncology and Beyond
“Advancing CAR-T Therapy: From Oncology to Novel Applications”
Virtual (Google Meet)
Mentor Based
Advanced
3 Days (1.5 hours per day)
18 – Dec – 24
3:00 PM IST
About
CAR-T therapy has revolutionized the field of oncology, offering personalized and highly effective treatments for certain cancers. This 3-day workshop dives deep into the biological principles behind CAR-T therapy, from T-cell engineering to antigen targeting, along with real-world applications and case studies in oncology. Participants will explore the full therapeutic landscape, including FDA-approved therapies and emerging treatments.
Beyond oncology, CAR-T therapy is now being explored for autoimmune diseases, infectious diseases, and other non-cancerous conditions. The workshop will discuss the future directions of CAR-T research and clinical trials, addressing the current hurdles in scaling these therapies. Participants will also engage in practical sessions, including CAR-T cell manufacturing, regulatory frameworks, and understanding the ethical considerations surrounding gene editing and cellular therapies.
Aim
This advanced workshop on “CAR-T Therapy: Oncology and Beyond” aims to provide a comprehensive understanding of Chimeric Antigen Receptor (CAR) T-cell therapy, its mechanisms, clinical applications, and future potential beyond oncology. Participants will gain insights into the latest developments, challenges, and innovations in CAR-T therapy for both cancer treatment and other emerging applications.
Workshop Objectives
- Understand the fundamentals of CAR-T cell biology and immunotherapy mechanisms.
- Explore CAR-T therapy applications in oncology and beyond.
- Learn about the latest innovations, clinical trials, and emerging applications.
- Gain practical knowledge of CAR-T cell manufacturing and regulatory requirements.
- Discuss ethical, safety, and scalability challenges in CAR-T therapy.
Workshop Structure
Day 1: Introduction to CAR-T Therapy
Workshop Overview
- Introduction to the workshop structure and objectives
- Importance of CAR-T therapy in modern oncology
Introduction to Immunotherapy
- What is immunotherapy?
- The role of the immune system in cancer treatment
- Overview of different immunotherapy approaches (Monoclonal antibodies, checkpoint inhibitors, CAR-T)
CAR-T Therapy Basics
- What is CAR-T (Chimeric Antigen Receptor T-cell) therapy?
- Mechanism of CAR-T: How it works (T-cell modification and cancer cell targeting)
- Historical development of CAR-T therapy
- Overview of FDA-approved CAR-T therapies (e.g., Kymriah, Yescarta, Breyanzi)
The Science Behind CAR-T
- T-cell biology and role in immune response
- CAR-T cell structure and function: Antigen recognition, CAR components
- Process of CAR-T cell therapy (from patient cell collection to infusion)
Clinical Indications of CAR-T Therapy
- Types of cancers treated with CAR-T (leukemia, lymphoma, etc.)
- Patient selection and eligibility criteria
- Success rates and key clinical outcomes
Q&A and Recap
- Open floor for questions
- Summary of key learnings from Day 1
Day 2: CAR-T Therapy Manufacturing and Clinical Applications
Recap of Day 1 and Key Takeaways
- Brief review of the fundamentals of CAR-T therapy
CAR-T Manufacturing Process
- Overview of the CAR-T cell production process
- Steps: T-cell collection, genetic modification (viral vectors), CAR-T expansion, and infusion
- Challenges in manufacturing (scalability, cost, and logistics)
- Ensuring safety and efficacy during production
- Automation and emerging trends in CAR-T manufacturing
Clinical Administration of CAR-T Therapy
- Patient preparation: Lymphodepleting chemotherapy
- The CAR-T infusion process
- Managing side effects and toxicities: Cytokine Release Syndrome (CRS), Neurotoxicity
- CAR-T monitoring and patient management post-infusion
- Long-term follow-up and remission rates
Real-World Case Studies
- Analysis of real-world CAR-T patient outcomes (success stories and challenges)
- Discussion of clinical trials and their significance in CAR-T advancements
- Case study presentations with interactive Q&A
Q&A and Recap
- Address any questions
- Summarize the session learnings
Day 3: Future Directions, Challenges, and Ethical Considerations
Recap of Day 2 and Key Takeaways
- Brief review of the CAR-T manufacturing and clinical process
Advancements and Innovations in CAR-T
- Next-generation CAR-T therapies: Dual-targeting CARs, armored CARs, and universal CAR-T cells
- CAR-NK and other cellular therapies in development
- Use of CAR-T beyond hematologic malignancies (solid tumors)
- Emerging technology: CRISPR and gene editing in CAR-T optimization
Overcoming Current Challenges
- Resistance to CAR-T therapy and relapse in patients
- Addressing high costs and accessibility issues
- Managing side effects more effectively
- Overcoming the complexity of treating solid tumors
Ethical and Regulatory Considerations
- Ethical challenges in gene-modified therapies (access, cost, and equity)
- Informed consent and patient education
- Regulatory pathways for CAR-T approval (FDA, EMA)
- Impact of CAR-T on the healthcare system (insurance coverage, cost of care)
Future of CAR-T: Looking Ahead
- Predictions for the next 5–10 years in CAR-T therapy
- Personalized medicine and the integration of AI and data in CAR-T treatment
- Potential for CAR-T in combination therapies
Open Discussion and Q&A
- Group discussion on the future of CAR-T
- Audience questions and expert responses
Conclusion and Wrap-Up
- Recap of the entire 3-day workshop
- Final thoughts and takeaways
Participant’s Eligibility
- Undergraduate or graduate degree in Biotechnology, Immunology, Biomedical Sciences, or related fields.
- Medical professionals, oncologists, and clinical researchers involved in cell-based therapies.
- Individuals with an interest in gene therapy, cellular therapies, or advanced medical treatments.
Important Dates
Registration Ends
2024-12-18
Indian Standard Timing
Workshop Dates
2024-12-18 to 2024-12-20
Indian Standard Timing 3:00 PM
Workshop Outcomes
- Master CAR-T cell biology and engineering principles.
- Gain insights into the clinical applications of CAR-T therapies in cancer and other diseases.
- Understand the regulatory and ethical frameworks governing CAR-T therapies.
- Acquire practical skills in CAR-T cell manufacturing and quality control.
- Explore future innovations and applications of CAR-T beyond oncology.
Mentor Profile
Designation: Director
Affiliation:
Mr. Himanshu Sehgal is a Director – Client Service and Project Delivery at the Octavus Consulting and PharmaShots Media. He received his MS Degree in ImmuDeactivatedlogy & Infectious Disease from University of Leeds, UK in 2012 and earned his management degree from Indian Institute of Management (IIM) LuckDeactivatedw and a diploma in InDeactivatedvation & Marketing strategy from London School of EcoDeactivatedmics. He has worked with PwC Intelligence, Deactivatedvartis and WNS for 9 years and held leadership roles with the said organization. He is having 12 Years of Experience in the field of Management consulting dedicatedly working for Pharma, Life sciences industry. His Area of Expertise includes: Competitive Intelligence, Market Research, Strategy planning, Product launch strategy, LCM Strategy and Business Analytics.
Fee Structure
Student
INR. 1399
USD. 50
Ph.D. Scholar / Researcher
INR. 1699
USD. 55
Academician / Faculty
INR. 2199
USD. 60
Industry Professional
INR. 2699
USD. 85
List of Currencies
Key Takeaways
- Access to Live Lectures
- Access to Recorded Sessions
- e-Certificate
- Query Solving Post Workshop
Future Career Prospects
- Immunotherapy Research Scientist
- Clinical Researcher in Oncology
- CAR-T Cell Therapy Specialist
- Regulatory Affairs Specialist in Biopharma
- Cell and Gene Therapy Manufacturing Expert
- Biotechnology Consultant
Enter the Hall of Fame!
Take your research to the next level!
Achieve excellence and solidify your reputation among the elite!
Related Courses
A Hands-On Program for Genomic …
Data Analysis – Use in AI
AI in Personalized Medicine
AI in Patient Monitoring and …
Recent Feedbacks In Other Workshops
Good
Need a elaborative and time to discuss with students